Metatissue® is focused on designing and manufacturing human protein-based products from cell culture to microtissue development and tissue/organ regeneration.
Our human protein-based systems are designed to increase the accuracy of in vitro studies by providing realistic microenvironments to cells.
The extracellular matrix of living tissues is composed of a great diversity of structural proteins and bioactive factors. For this reason, mimicking its function in vitro continues to be a big challenge. Our strategy is to use ethically sourced human proteins to produce the next-generation of biomimetic 3D cell culture platforms.
Reduce drug discovery costs and time to market
Reduce animal testing
Personalized healthcare products
Provides xeno-free platforms produced from ethically and easy available human sources that are chemically modified to prepare robust and easy to handle materials for cell culture.
Cell Growth and expansion
Tissue morphogenesis
and homeostasis
Platform that support tissue regeneration
Drug discovery and screening
The potential the Metatissue’s technology to reduce or completely replace use of animals for biological screenings will have a significant impact in the 3D cell culture market and pharmaceutical industry by accelerating drug screening and development reducing associated costs.
Our aim is to improve the correlation between laboratorial research and clinical trials, while reducing animal testing and increasing the speed of scientific discoveries.
Multiple native human derived proteins and growth factors provide a xeno-free alternative to animal derived products.
The materials are prepared from multiple donor units that are pooled to minimize lot-to-lot variability.
Under request, specific products may be prepared with samples from a specific donor, enriched or depleted in specific target molecules.
The mechanical properties can be easily adjusted by controlling the amount of proteins or degree of modification.
Easily processed in multiple geometries and in microarrays amenable to ‘organ-on- a chip’ systems designed for high-throughput screening (HTS) applications
Our aim is to improve the correlation between laboratorial research and clinical trials, while reducing animal testing and increasing the speed of scientific discoveries.
Multiple native human derived proteins and growth factors provide a xeno-free alternative to animal derived products.
The materials are prepared from multiple donor units that are pooled to minimize lot-to-lot variability.
Under request, specific products may be prepared with samples from a specific donor, enriched or depleted in specific target molecules.
The mechanical properties can be easily adjusted by controlling the amount of proteins or degree of modification.
Easily processed in multiple geometries and in microarrays amenable to ‘organ-on- a chip’ systems designed for high-throughput screening (HTS) applications
João F. Mano (CEng, PhD, DSc) is a Full Professor at the Chemistry Department of the University of Aveiro and Principal Investigator at CICECO
Catarina Custódio graduated in Applied Chemistry at FCT-UNL. In 2013 she received her PhD degree in Tissue Engineering
Clara Correia is a post-doctoral research fellow aiming to develop self-regulated microencapsulation systems for tissue regeneration.
Ana Sofia Silva is a BSc and MSc in Biomedical Sciences from University of Beira Interior and a PhD in Bioengineering from NOVA
Via do Conhecimento, Edifício Central
3830-352 Ílhavo, Portugal
info@metatissue.com
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